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University of Graz News Leistbare Medizin: Uni Graz heimst 330.000-Euro-Förderung ein

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Tuesday, 18 July 2023

Leistbare Medizin: Uni Graz heimst 330.000-Euro-Förderung ein

Oliver Kappe und David Cantillo im Labor am Institut für Chemie ©Uni Graz/Tzivanopoulos

Oliver Kappe (l.) und David Cantillo setzen elektrochemische Verfahren zur Produktion von nachhaltigen und kostengünstigen Medikamenten ein. Dafür erhielten sie eine 330.000-Euro-Förderung. Foto: Uni Graz/Tzivanopoulos

Oliver Kappe und David Cantillo haben eine Finanzierung der Bill & Melinda Gates Foundation an Land gezogen. Sie erforschen eine Herstellungsmethode für Medikamente mithilfe der Elektrochemie.

Arzneimittel klimaschonend zu produzieren und vor allem für ärmere Länder verfügbar zu machen, ist den Uni-Graz-Forschern C. Oliver Kappe und David Cantillo gelungen. Sie haben elektrochemische Verfahren entwickelt, die deutlich billiger und umweltfreundlicher sind als herkömmliche Methoden. Von der Bill & Melinda Gates Foundation haben sie nun für zwei Jahre knapp 360.000 US-Dollar – umgerechnet rund 330.000 Euro – erhalten, um einen nachhaltigen Herstellungsweg für Tuberkulose-Medikamente zu finden.

„Wir verwenden Elektronen anstelle von umweltschädlichen Chemikalien, die am Ende des Herstellungsprozesses teuer entsorgt werden müssen“, fasst Kappe das Prinzip der Technologie zusammen. Sein Kollege Cantillo hat dafür einen Reaktor entwickelt, der auch dickflüssiges Material verarbeiten kann. Eine weitere wissenschaftliche Herausforderung für das Team ist nun, Wege zu finden, um die benötigten Moleküle mit der neuen Methode richtig „zusammenzubauen“. Konkret forschen die Chemiker:innen der Universität Graz an den Wirkstoffen Delamanid und Pretomanid, die für die Behandlung von arzneimittelresistenter Tuberkulose eingesetzt werden.

created by Dagmar Eklaude

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