Institute of Chemistry, University of Graz, Austria

























Recent Hot Papers from the Kappe Lab:



In Situ Generation of Diimide from Hydrazine and Oxygen - Transfer Hydrogenation of Olefins in Continuous Flow.

B. Pieber, S. T. Martinez, D. Cantillo, C. O. Kappe

Angew. Chem. Int. Ed. 2013, 52, 1042


Continuous Flow Generation and Reactions of Anhydrous Diazomethane Using a Teflon AF-2400 Tube-in-Tube Reactor
F. Mastronardi, B. Gutmann, C. O. Kappe,
Org. Lett. 2013, 15, 5590


Shifting Chemical Equilibria in Flow – Efficient Decarbonylation Chemistry Driven by Annular Flow Regimes.

B. Gutmann, P. Elsner, T. Glasnov, D. M. Roberge, C. O. Kappe

Angew. Chem. Int. Ed. 2014, 53, 11557


Continuous Flow Reduction of Artemisinic Acid Utilizing Multi-Injection Strategies – Closing the Gap Towards a Fully Continuous Synthesis of Antimalarial Drugs

B. Pieber, T. Glasnov, C. O. Kappe

Chem. Eur. J. 2015, 21, 4368


Use of Continuous Flow Technology to Harness Hazardous Chemistries and Process Conditions – A Tool for the Manufacturing of Active Pharmaceutical Ingredients (Review)

B. Gutmann, D. Cantillo, C. O. Kappe

Angew. Chem. Int. Ed. 2015, 54, 6688



Press Room:

Christian Doppler Laboratory for Microwave Chemistry wins 100.000 € Dr. Wolfgang Houska Prize


Christian Doppler Laboratory for Flow Chemistry Starts Operation



2004 Angewandte Chemie Review on Microwave Chemistry hits 2000 Citations

link (in german)


The Kappe Lab in the Press:


New Stirring Design for Microwaves

Chemistry World Article


Author Profile - Angewandte Chemie


Microwave Quarrel Heats Up

Chemistry World Article


Diazomethane without Tears. Or Explosions

Blog: Corante - In the Pipeline


An Interview with C. O. Kappe

Chemistry World Interview


Microwave Effects Debate

Chemical Engineering News Article


Artemisinin Flow Synthesis

Chemical Engineering News Article


Further Press Coverage (link)