List of Publications Prof. Dr. Andreas Zimmer
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Research Papers:

	Herzfeldt C.-D., Zimmer A., and Brehm R., An automated modified half-change-test for extended-release articles Pharmazeutische Industrie 49 (1987) 948-951.
	Herzfeldt C.-D., Hellenbrecht D., Zimmer A., and Brehm R., Poor availability of sustained-release theophylline caused by pH-dependent biphasic release Acta Pharmaceutica Technologica 35 (1989) 79-81.
	Zimmer A., Kreuter, J., and Robinson, J. R., Studies on the transport pathway of PBCA nanoparticles in ocular tissues J Microencapsulation 8 (1991) 497-504.
	Bertling, W. M., Gareis, M., Paspaleeva, V., Zimmer A., Kreuter, J., Nürnberg, E., and Harrer, P., Use of liposomes, viral capsids, and nanoparticles as DNA carriers Biotech Appl Biochem 13 (1991) 390-405.
	Langer, K., Seegmüller, E., Zimmer A., and Kreuter, J., Characterisation of polybutylcyanoacrylate nanoparticles: I. Quantification of PBCA polymer and dextrans Int J Pharm 110 (1994) 21-27.
	Zimmer A., Mutschler, E., Lambrecht, G., Mayer, D., and Kreuter, J., Pharmacokinetic and pharmacodynamic aspects of an ophthalmic pilocarpine nanoparticle-delivery-system Pharm Res 11 (1994) 1435-1442.
	Pirker, S., Kruse, J., and Noe, C., Langer, K., Zimmer A., Kreuter, J., Characterization of polybutyleyanoacrylate nanoparticles. Part II: Determination of polymer content by NMR-analysis Int J Pharm 128 (1996) 189-195.
	Zobel H.-P., Kreuter J., Werner D.,Kümel G., Noe C.R. and Zimmer A., Cationic polyhexylcyanoacrylate nanoparticles as carrier for antisense-oligonucleodides Antisense Nucleic Acid Drug Dev (1997) 483-493.
	Braun H., Boller K., Löwer J., Bertling W.M., and Zimmer A., Oligonucleotide and plasmid DNA packaging into polyoma VP1 virus-like-particles expressed in E.coli Biotechnol Appl Biochem 29 (1999) 31-43.
	Zimmer A., Atmaca-Abdel Aziz S., Gilbert M., Werner D., Noe C.R., Synthesis of cholesterol modified cationic lipids for liposomal drug delivery of antisense oligonucleotides Eur J Pharm Biopharm 47 (1999) 175-178.
	Zobel H.-P., Zimmer A., Atmaca-Abdel Aziz S., Gilbert M., Werner D., Noe C.R., Kreuter J., Stieneker F., Evaluation of Aminoalkylmethacrylate Nanoparticles as Colloidal Drug Carrier Systems. Part I: Synthesis of Monomers, Dependence of the Physical Properties on the Polymerization Methods Eur J Pharm Biopharm 47 (1999) 203-213.
	Zobel H.-P., Stieneker F., Atmaca-Abdel Aziz S., Gilbert M., Werner D., Noe C.R., Kreuter J., and Zimmer A., Evaluation of Aminoalkylmethacrylate Nanoparticles as Colloidal Drug Carrier Systems. Part II: Characterisation of Antisense Oligonucleotides loaded Copolymer Nanoparticles Eur J Pharm Biopharm 48 (1999) 1-12.
	Zobel H.-P., Stieneker F., Werner D., Gilbert M., Noe C.R., Kreuter J., and Zimmer A., Effect of ultrasonication on the stability of oligonucleotides J Microencapsulation 16 (1999) 501-509.
	Zimmer A., Antisense oligonucleotide delivery with polyhexylcyanoacrylate nanoparticles as carriers Methods: A Companion to Methods in Enzymology 18 (1999) 286-295.
	Henke S., Rohmann A., Bertling W.M., Dingermann Th., and Zimmer A., Enhanced in vitro oligonucleotide and plasmid DNA transport by VP1 virus-like particles Pharm Res 17 (2000) 1062-1070.
	Zobel H.-P., Junghans M., Maienschein V., Werner D., Gilbert M., Zimmermann H., Noe C.R., Kreuter J., and Zimmer A., Enhanced antisense efficacy of oligonucleotides adsorbed to monomethylaminoethylmethacrylate methylmethacrylate copolymer nanoparticles Eur J Pharm Biopharm 49 (2000) 203-210.
	Junghans M., Kreuter J., and Zimmer A., Antisense delivery using protamine - oligonucleotide - particles Nucleic Acids Res 28 (2000) E45.
	Delie F., Gurny R., and Zimmer A., Fluorescence correlation spectroscopy for the characterisation of drug delivery system Biol Chem 382 (2001) 487-490.
	Junghans M., Kreuter J., and Zimmer A., Phosphodiester and phosphorothioate oligonucleotide condensation and preparation of antisense nanoparticles BBA [Protein Structure and Molecular Enzymology] 1544 (2001) 177-188.
	Rohmann, A., Lochmann, D., Weyermann, J., Bertling, W. M., Dingermann, T., and Zimmer A. Rapid screening method for antisense oligonucleotides against human growth factor receptor p185(erbB-2) Oligonucleotides 14 (2004) 1-9.
	Dinauer, N., Lochmann, D., Demirhan, I., Bouazzaoui, A., Zimmer A., Chandra, A., Kreuter, J., and von Briesen, H., Intracellular tracking of protamine/antisense oligonucleotide nanoparticles and their inhibitory effect on HIV-1 transactivation J Control Release 96 (2004) 497-507.
	Weyermann, J., Lochmann, D., Georgens, C., Rais, I., Kreuter, J., Karas, M., Wolkenhauer, M., and Zimmer A. Physicochemical characterisation of cationic polybutylcyanoacrylate-nanoparticles by fluorescence correlation spectroscopy Eur J Pharm Biopharm 58 (2004) 25-35.
	Budai, M., Szabó, Z., Szögyi, M., Gróf, P., and Zimmer A., Studies on molecular interactions between nalidixic acid and liposomes Int J Pharm 279 (2004) 67-79.
	Lochmann, D., Weyermann, J., Kreuter, J., Vogel, V., Schubert, D., Dinauer, N., Von Briesen, H., and Zimmer A., Physicochemical characterization of protamine-phosphorothioate nanoparticles J Microencapsulation 21 (2004) 625-641.
	Lochmann, D., Stadlhofer, S., Weyermann, J., and Zimmer A., New protamine quantification method in microtiter plates using o-phthaldialdehyde/N-acetyl-L-cysteine reagent Int J Pharm 283 (2004) 11-17.
	Weyermann, J., Lochmann, D., and Zimmer A., Comparison of antisense oligonucleotide drug delivery systems J Control Release 100 (2004) 411-423.
	Weyermann, J., Lochmann, D., and Zimmer A., A practical note on the use of cytotoxicity assays Int J Pharm 288 (2005) 369-376.
	Vogel, V., Lochmann, D., Weyermann, J., Mayer, G., Tziatzios, C., van den Broek, J. A., Haase, W., Wouters, D., Schubert, U. S., Kreuter, J., Zimmer A., and Schubert, D., Oligonucleotide-protamine-albumin nanoparticles: preparation, physical properties, and intracellular distribution J Control Release 103 (2005) 99-111.
	Lochmann, D., Weyermann, J., Georgens, C., Prassl, R., and Zimmer A., Albumin-protamine-oligonucleotide nanoparticles as a new antisense delivery system. Part 1: Physicochemical characterization Eur J Pharm Biopharm 59 (2005) 419-429.
	Weyermann, J., Lochmann, D., Georgens, C., and Zimmer A., Albumin-protamine-oligonucleotide-nanoparticles as a new antisense delivery system. Part 2: cellular uptake and effect Eur J Pharm Biopharm 59 (2005) 431-438.
	Michaelis, M., Zimmer A., Handjou, N., Cinatl, J., and Cinatl, J.Jr. Increased systemic efficacy of aphidicolin encapsulated in liposomes Oncol Rep 13 (2005) 157-160.
	Junghans M., Loitsch S.M., Steiniger S., Kreuter J., and Zimmer A., Cationic lipid–protamine–DNA (LPD) complexes for delivery of antisense c-myc oligonucleotides Eur J Pharm Biopharm (2005) 287-294.
	Mayer G., Vogel V., Weyermann J., Lochmann D., van den Broek J. A., Tziatzios C., Haase W., Wouters D., Schubert U. S., Zimmer A., Kreuter J., and Schubert D., Oligonucleotide-protamine-albumin nanoparticles: Protamine sulfate causes drastic size reduction J Control Release 106 (2005) 181-187.
	Kerkmann M., Lochmann D., Weyermann J., Marschner A., Poeck1 H., Wagner M., Zimmer A., Endres S., Hartmann G. Immunostimulatory properties of CpG-oligonucleotides are enhanced by the use of protamine nanoparticles Oligonucleotides 16 (4) (2006) 313-322.
	Kratzer I., Wernig K., Panzenboeck U., Bernhart E., Reicher H., Wronski R., Windisch M., Hammer A., Malle E., Zimmer A., Sattler W. Apolipoprotein A-I coating of protamine-oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood-brain barrier J Control Release 117 (2007) 301-311.
	Graf A., Ablinger E.; Peters S., Zimmer A., Hook S. and Rades Th. Microemulsions containing lecithin and sugar-based surfactants: Nanoparticle templates for delivery of proteins and peptides Int. J. Pharm. 350 (2008) 351-360.
	Budai M., Gróf P., Zimmer A., Pápai K., Klebovich I. and Ludányi K UV light induced photodegradation of liposome encapsulated fluoroquinolones: an MS study J Photochem 198 (2008) 268-273.
	Wernig K., Griesbacher M., Andreae F., Hajos F., Wagner J., Mosgoeller W. and Zimmer A. Depot formulation of Vasoactive Intestinal Peptide by protamine-based biodegradable nanoparticles J Control Rel 130 (2008) 192-198.
	Kaszás N., Budai M., Budai L, Gróf P., Zimmer A., Klebovich I. Methods to increase the encapsulation efficiency for liposomal drugs Acta Pharm Hungarica 78 (2008) 69-74.
	Schicher M., Polsinger M., Hermetter A., Prassl R. and Zimmer A. In vitro release of Propofol and binding capacity with regard to plasma constitutents Eur J Pharm Biopharm 70 (2008) 882-888.
	Budai M., Chapela P., Grof P., Zimmer A., Wales M., Wild JR., Klebovich I., Petrikovics I. and Szilasi M. Physicochemical characterization of stealth liposomes encapsulating an organophosphate hydrolyzing enzyme J Liposome Res. 23 (2009) 1-6.
	Budai M., Chapela P., Budai L., Wales M., Petrikovics I., Zimmer A., Grof P., Klebovich I. and Szilasi M. Liposomal oxytetracycline and doxycycline: studies on enhancement of encapsulation efficiency Drug Discov Ther (2009) 13-17.
	Fröhlich E., Samberger C., Kueznik T., Absenger M., Roblegg E., Zimmer A. and Pieber Th. R. Cytotoxicity of nanoparticles independent from oxidative stress J Toxicol Sci 34 (2009) 363-375.
	Roblegg E., Sinner F. and Zimmer A. Health Risks of Nanotechnology Euro Nanotox Letters (2009) 1-18.
	Roblegg E., Ulbing S., Zeissmann S., and Zimmer A. Development of lipophile calcium stearate pellets using ibuprofen as model drug EJPB 75 (1) (2010) 56-62.
	Ortner A., Wernig K., Kaisler R., Edetsberger M., Hajos F., Köhler G., Mosgoeller W., and Zimmer A. VPAC receptor mediated tumour cell targeting by protamine based nanoparticles J Drug Target 18 (6) (2010) 457-467.
	Roblegg E., Dittrich P., Haltmeyer K., and Zimmer A. Reformulation of a codeine phosphate liquid controlled release product DDIP 36 (12) (2010) 1454-1462.
	Voura, C., Gruber, M.M., Schroedl, N., Eitzinger, B., Bauer, W., Brenn, G., Khinast, J.G., Zimmer A. Printable Medicines - A Microdosing Device for the Production of Personalized Oral Dosage Forms Pharmaceutical Technology Europe 23 (1) (2011) 32-36.
	Dittrich, P., Beubler, E., Haltmeyer, K., and Zimmer A., Roblegg E. Pharmacokinetics of a Novel Liquid Controlled Release Codeine Formulation Drug Development and Industrial Pharmacy (2011)
	Almer G., Wernig K., Saba-Lepek M., Haj-Yahya S., Rattenberger J., Wagner J., Gradauer K., Frascione D., Pabst G., Leitinger G., Mangge H., Zimmer A., Prassl R. Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques International Journal of Nanomedicine 6 (2011) 1279-1290.
	Pardeike, J., Weber, S., Haber, T., Wagner, J., Zarfl, H.P., Plank, H., Zimmer A. Development of an Itraconazole-loaded Nanostructured Lipid Carrier (NLC) formulation for pulmonary application International Journal of Pharmaceutics 419 (2011) 329– 338.
	Roblegg, E., Schrank S., Griesbacher M., Radl S., Zimmer A., and Khinast J. Use of the Direct Compression Aid Ludiflash® for the Preparation of Pellets via Wet Extrusion/Spheronization Drug Development and Industrial Pharmacy 37 (2011) 1231-1243.
	Eitzlmayr A., Petschacher Ch., Radl S., Suzzi D., Zimmer A., Khinast J.G. Modeling and Simulation of Polyacrylic acid/Protamine Nanoparticle Precipitation Soft Matter 7 (2011) 9484-9497.
	Roblegg E., Jäger E., Hodzic A., Koscher G., Mohr S.,Zimmer A., Khinast J. Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion European Journal of Pharmaceutics and Biopharmaceuticsr 79 (2011) 635–645.
	Pardeike, J., Strohmeier, D., Schrödl, N., Voura, C., Gruber, M., Khinast, J.G., Zimmer A. Nanosuspensions as advanced printing ink for accurate dosing of poorly soluble drugs in personalized medicines International Journal of Pharmaceutics 420 (2011) 93-100.
	T. Paukert, R. Sailer, W. S. L. Strauss, M. Schubert-Zsilavecz, Zimmer A. Glutathione peroxidase isoenzymes in human tumor cell lines Die Pharmazie 66 (2011) 894-898.
	Roblegg, E., Falk, A., Fröhlich, E., Zimmer A., and Sinner, F. European Centre for Nanotoxicology: A Proactive Risk-assessment Nanotechnology lnitiative Academy of Science Malaysia Journal, 5 (1) (2011) 43-52.
	Roblegg E., Samberger C., Zaversky M., Zimmer A.,, Fröhlich, E. , Roblegg E. Evaluation of a physiological in-vitro system to study the transport of nanomaterials through the buccal mucosa Nanotoxicology (2011) in press
	Pardeike, J., Weber, S., Zarfl, H.P., Pagitz, M., Zimmer A. Itraconazole-loaded Nanostructured lipid carriers (NLC) for pulmonary treatment of Aspergillosis in falcons (2011) submitted
	Mosgoeller W., Prassl R., Zimmer A. Nanoparticle-mediated treatment of pulmonary arterial hypertension Methods in Enzymology (2011) accepted

Reviews:

	Zimmer A., and Kreuter, J. Microspheres and nanoparticles used in ocular delivery systems Adv Drug Deliv Rev 16 (1995) 61-73.
	Zimmer A., and Herzfeldt, C.-D. Formulae of sunscreens from the pharmacy [Galenik apothekenüblicher Sonnenschutzmittel] PZ Prisma 4 (1997) 173-184.
	Langer, K., Zimmer A., and Kreuter, J. Acrylic nanoparticles for ocular drug delivery S.T.P. Pharma Sciences 7 (1997) 445-451.
	Zimmer A. Galenic formulation of recombinant drugs [Galenische Formulierung rekombinanter Wirkstoffe] Pharmazie in Unserer Zeit 32 (2003) 384-389.
	Lochmann, D., Jauk, E., and Zimmer A., Drug delivery of oligonucleotides by peptides Eur J Pharm Biopharm 58 (2004) 237-251.
	Georgens, C., Weyermann, J., and Zimmer A., Recombinant virus like particles as drug delivery system Curr Pharm Biotechnol 6 (2005) 49-55.
	Reischl D. and Zimmer A. Drug delivery of siRNA therapeutics: Potentials and limits of nanosystems J Nanomed 5 (2009) 8-20
	Stegemann S., Ecker F., Maio M., Kraahs P., Wohlfart R., Breitkreuz J., Zimmer A., Bar-Shalom D., Hettrich P., and Broegmann B. Geriatric drug therapy: neglecting the inevitable majority Ageing Res Reviews 9 (4) (2010) 384-398
	Burian B., Ortner A., Prassl R., Zimmer A., Mosgoeller W. Clinical potential of VIP by modified pharmako-kinetics and delivery mechanisms Endocrine, Metabolic & Immune Disorders - Drug Targets (2011) in press

Patents:

	Noe C., Kreuter J., Zimmer A., Zobel H-P., Stieneker F., Atmaca-Abdel Aziz S., Partikuläre Arzneiform EP 0808174 B1 (1996)
	Zimmer A., Zobel H-P., Stieneker F., Atmaca-Abdel Aziz S., Medicament in particle form WO9624377 A1 (1996)
	Junghans M., Zimmer A., und Kreuter J. Synthetisches Nucleinsäurepartikel DE 198 58 005 A1 (1998)
	Junghans M., Zimmer A., und Kreuter J. Synthetic Nucleic Acid Particle EP 1 141 367 B8 (1999)
	Zimmer A., Wernig K., Wegscheider S., und Matous H. Stabilisierte Flüssigformulierung EP 08008085.6. (2008) in process
	Berhart E., Eder H., Mrfka M., Sattler W., Zimmer A., Reischl D. Compounds reducing or inhibiting the expression of PKD1 for diagnosis and therapy of brain tumors EP 08157734.8 (2008) in process
	Khinast J., Brenn G., Zimmer A., Eichinger R., Bauer W. A system and method for manufacturing a medication EP 08 013 696.3. (2008) in process

Books and Book Chapters:

	Zimmer A. Herzfeldt C.-D. CompaSys Dermatika Govi-Verlag GmbH Pharmazeutischer Verlag (1990) ISBN: 3-7741-0222-8.
	Zimmer A. Herzfeldt C.-D. InfoSys Sonnenschutz Govi-Verlag GmbH Pharmazeutischer Verlag (1991) ISBN: 3-7741-0226-X.
	Zimmer A. Herzfeldt C.-D. InfoSys Sonnenschutz Govi-Verlag GmbH Pharmazeutischer Verlag (1992) ISBN: 3-7741-0267-8.
	Zimmer A. Pharmacokinetics and pharmacodynamics of pilocarpine loaded PBCA- nanoparticles in the glaucomatous rabbit eye Shaker, Aachen (1993) ISBN 3-86111-577-8.
	Zimmer A. and Attwood D. Mikroemulsionen J. Kreuter & C.-D. Herzfeldt (Eds.) Arzneiformenlehre - Galenik II Springer Verlag, Heidelberg (1999) ISBN 3-540-65291-4.
	Roblegg E. und Zimmer A. Wichtige Arzneiformen der nicht-opioiden Analgetika, in: E. Beubler (Ed.) Nicht-opioide Analgetika Versuch einer Neubewertung Uni-Med Science, Bremen (2006) ISBN 978-3-89599-994-9.
	Roblegg E. und Zimmer A. Virus-based Nanoparticles as Drug Delivery Systems Polymeric Biomaterials III Ed. (2011) accepted

Peer-reviewed Abstracts and Reports:

	Zimmer A., and Herzfeldt, C.-D. CompaSys: An information system for drug tolerance [COMPASYS: INFORMATIONSSYSTEM FUR GALENISCHE VERTRAGLICHKEIT] Pharm Ztg 135 (1990) 56-58.
	Zimmer A., Zimmer A.K., and Kreuter, J. 'Used' drugs in pharmacies [RÜCKLAUF VON ALT-ARZNEIMITTELN IN APOTHEKEN] Pharm Ztg 137 (1992) 20-29.
	Zimmer A., Zobel, H.-P., Werner, D., Noe, C. R., and Kreuter, J. Cationic nanoparticles as enhancers for cellular uptake of antisense oligonucleotides Proceedings of the Controlled Release Society (24) (1997) 679-680.
	Zobel, H.-P., Brinkmann, I., Förstl, B., Heim, S., Müller, C., Van Nguyen, T. H., Prescher, K., and Zimmer A. A comparative alternative to classical ointment production at the pharmacy [Alternativen zum Salbenrühren im Vergleich] Pharm Ztg 142 (1997) 24-25+28.
	Zimmer A., Delie-Salmon, F., and Gurny, R. Application of fluorescence correlation spectroscopy for the characterisation of drug delivery systems Proceedings of the Controlled Release Society (26) (1999) 563-564.
	Zimmer A., Kreuter J., Graeser U., and Wakolbinger A. Study of expired drugs [Altarzneimittelstudie] Pharm Ztg 3 (1999) 23-29.
	Deml A., Jennes I., Küster C., Preißmann M., Wingerter O., and Zimmer A. Insulin pumps [Insulinpumpen] Deutsche Apoth Ztg 140 (2000) 56-62.
	Deutschmann B., Zimmer A. and Presser A. Darstellung funktionalisierter Cholesterolderivate zum selektiven Transport von Antisense Oligonukleotiden in Hepatozyten Scientia Pharmaceutica 71 (2003) 31.
	Budai M., Pallaghy R., Szabo Zs., Zimmer A., Grof P. Liposome encapsulated fluoroquinolones: An EPR- and DLS-study Europ J Pharm Sci. 25 (2005) S64-S66 .
	Polsinger M., Reiter F., Stabentheiner E., Zimmer A. Controlled drug delivery systems based on ion - Exchange resins Europ J Pharm Sci. 25 (2005) S175-S176.
	Kratzer I., Wernig K., Bernhart E., Panzenbock U., Wronski R., Windisch M., Zimmer A. and Sattler W. Uptake of oligonucleotide-protamine nanoparticles by brain capillary endothelial cells Chemistry and Physics of Lipids 143 (2006) 110-111.
	Roblegg E., Sinner F. Zimmer A. Health Risks of Nanotechnology [Gesundheitsrisiken der Nanotechnologie] www.nanoinitiative.at (2007)
	Schrank, S., Khinast, J., Zimmer A., Roblegg, E. Entwicklung eines Extrusions-Spheronisationsprozesses zur Herstellung von rasch zerfallenden Pellets Tagungsband Chemie Ingenieur Technik, Verlag WILEY-VCH Verlag, Weinheim 82(9) (2010) 1467.
	Stegemann S., Rasenack H., Ecker F., Zimmer A. Geriatrische Arzneimitteltherapie: Gesellschaftliche Herausforderung und pharmazeutische Lösungsansätze Deutsche Apotheker Zeitung 31 (2011) 44-58.

Reports (non peer-reviewed):

-	Zimmer A., und Herzfeldt C.-D. EDV in der Apotheke Beratungsprogramme II. Informationssystem galenische Verträglichkeit - CompaSys Dermatika. PTA in der Apotheke 21 (1992) 338-341.
-	Zimmer A., und Herzfeldt C.-D. Pharmazie: InfoSys Sonnenschutz. Pharm Ztg 137 (1992) 24-28.
-	Zimmer A., und Herzfeldt C.-D. EDV - Einsatz im Handverkauf. Pharm Ztg 138 (1993) 24-28.
-	Zobel H.-P., Brinkmann I., Förstel B., Heim S., Müller Ch., Nguyen Th.H.V., Prescher K. and Zimmer A. Das Unguator-Rührsystem (URSY) als Alternativverfahren zur Salbenherstellung. Der Deutsche Dermatologe, 6 (1998) 545-549.
-	Haltmeyer K., Roblegg E., Zimmer A. und Dittrich P., In-vitro-Freisetzung von Diclofenac - Arzneispezialitäten mit Dual-Release-System. ÖAZ 56 (2002) 806-807.
-	Leutgöb G., Stabentheiner E., and Zimmer A., Physikalische Charakterisierung schnell zerfallender oraler Arzneiformen. Partikelwelt 5 (2005).

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